MULTIDRUG-RESISTANT STRAINS OF BACTERIA RESPONSIBLE FOR FOODBORNE SALMONELLOSIS: PREVALENCE, MOLECULAR CHARACTERIZATION, AND PROPOSED THERAPEUTIC FORMULATIONS BASED ON TRADITIONAL BENINESE PLANTS

2016

Period :

2016 - 2019

1. Context

The recurrence of multi-resistance strains in clinical settings is becoming a cause for concern. This
situation is leading to numerous treatment failures in healthcare facilities. The
role of diet in the outbreak of multi-resistant strains is being increasingly
investigated. Faced with the threat posed by typhoid fever among the populations of Benin,
there is an urgent need to control this enteric disease, which is often
foodborne.

2. Objectives

General Objective

Optimizing the fight against enteropathogens responsible for salmonellosis in slaughter animals.
.

Specific Objectives

- Master the phenotypic, genotypic, and epidemiological aspects of enteropathogens responsible for salmonellosis in slaughter animals in southern Benin, - Produce scientific data on plants in the Beninese pharmacopoeia that are useful in the treatment of salmonellosis, - Evaluate the antibacterial properties of plants from southern Benin on strains of Salmonella spp.

3. Résultats Essentiels

- The prevalence and genetic characteristics of multidrug-resistant strains of Salmonella spp. in farms and slaughterhouses in southern Benin are known in southern Benin. - Traditional plants from southern Benin that are effective against these strains are mapped and tested.

4. Livrables

- At the end of the project, a traditionally improved medicine called SALM-MTA was proposed for use against gastroenteritis and salmonellosis. - Seven articles published on the project in indexed journals with impact factors.

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MULTIDRUG-RESISTANT STRAINS OF BACTERIA RESPONSIBLE FOR FOODBORNE SALMONELLOSIS: PREVALENCE, MOLECULAR CHARACTERIZATION, AND PROPOSED THERAPEUTIC FORMULATIONS BASED ON TRADITIONAL BENINESE PLANTS